And it's wonderful to see that our alumnus Gary Tin and the amazing Georg Winter wrote the News & Views piece on this paper!
#gunningalumni https://www.nature.com/articles/s41589-022-01217-x
CIDE-stepping E3s - Nature Chemical Biology
Small-molecule-mediated targeted protein degradation (TPD) relies on the recruitment of a target protein of interest to an E3 ligase. A new study indicates how direct target recruitment to the 26S proteasome can bypass this requirement.
Gunning Group