An #OpenSource #automated single-molecule #FRET platform for high-content, #multiwell #plate #screening of #biomolecular #conformations & #dynamics:
Article: https://doi.org/10.1038/s41467-023-42232-3
#autoFRET data analysis: https://github.com/SchlierfLAB/autoFRET
#DIYbio #lab #instruments #imaging
"In addition, while the capsid is associated with budding initiation, it is not required for curvature formation. By determining the NEC structure in several #conformations, we show that curvature arises from an asymmetric assembly of disordered and hexagonally ordered lattice domains independent of pUL25 or other #viral #capsid vertex components. Our results advance our understanding of the mechanism of nuclear egress in the context of a living cell."
Bose-Einstein-Kondensat
katch wreck