#NewGeneticEngineering #NGTs #WeKnowTheDifference

Testbiotech presents a comprehensive analysis of the deregulation proposal as part of the @EU_Commission's consultation.

In short: The technical potential, but also the technical shortcomings of tools such as #CRISPR/Cas make it necessary that all #geneticallyengineered organisms continue to be subject to an in-depth #riskassessment in the future.

https://www.testbiotech.org/en/news/testbiotech-warns-about-far-reaching-deregulation-new-ge-plants

Testbiotech warns about the far-reaching deregulation of New GE plants

31 August 2023 / Testbiotech has today published a comprehensive analysis of the EU Commission proposal for the future deregulation of plants obtained from new genetic engineering (New GE or NGT). This is part of an EU-wide consultation. Currently, all organisms derived from genetic engineering processes must undergo risk assessment before they can be released, cultivated or consumed as food. The Commission now wants to abandon this basic principle of EU legislation. Testbiotech, however, is warning against such far-reaching deregulation.

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#NewGeneticEngineering #WeKnowTheDifference

Example 7: Mustard greens was made less pungent with #NewGE. #CRISPR was used to alter 17 genes in the plant genome in parallel.

With the loss of pungency, substances considered to be particularly valuable for health were also lost. The scientists describe that gene sequences were inadvertently rearranged and recombined. An examination of the health risks did not take place.

https://www.testbiotech.org/en/limits-to-biotech/defused-mustard/basic_paper

CRISPR mustard as a salad

Brassica juncea is grown worldwide for use in oil and mustard production. It is able to spread in the environment and can be hybridized with related species; it is pollinated by insects. The plants naturally produce substances known as glucosinolates, which act as a defence against pests and are also known to be associated with health benefits.Pairwise used CRISPR/Cas to intervene in the metabolism of the glucosinolates and knock out specific gene functions of an enzyme. As a result, the leaves are less pungent.

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