Ron Beavis ❌UCP5 is also found in the central nervous system of both species, with a surprise appearance in sperm/testis in humans. The role of the protein has been as a hypothetical regulator of reactive oxygen species (Ramsden 2012 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432969) & more recently as an anion transporter (Gorgolione 2019 https://www.sciencedirect.com/science/article/pii/S0005272819300945)
Human & mouse uncoupling protein 5 (#UCP5:p | #SLC25A14:p)―GPMDB tissue tabbulations #proteomics #uncoupling
Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction
Uncoupling proteins (UCPs) belong to a large family of mitochondrial solute carriers 25 (SLC25s) localized at the inner mitochondrial membrane. UCPs transport protons directly from the intermembrane space to the matrix. Of five structural homologues (UCP1 ...