Luisa N. Borrell#TargetTrial and observational data for cancer research. #epitwitter #epiverse
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RT @_MiguelHernan
The European Organisation for Research and Treatment of Cancer (@EORTC) endorses #TargetTrial emulation with #RWD.
An organization with unmatched expertise in the design of #randomizedtrials embraces their explicit emulation when using observational data.
https://www.ejcancer.com/article/S0959-8049(23)00149-1/fulltext
https://twitter.com/_MiguelHernan/status/1638259606072750094
Defining the role of real-world data in cancer clinical research: the position of the European Organisation for Research and Treatment of Cancer
The emergence of the precision medicine paradigm in oncology has led to increasing interest in the integration of real-world data (RWD) into cancer clinical research. As sources of real-world evidence (RWE), such data could potentially help address the uncertainties that surround the adoption of novel anticancer therapies into the clinic following their investigation in clinical trials. At present, RWE-generating studies which investigate antitumor interventions seem to primarily focus on collecting and analyzing observational RWD, typically forgoing the use of randomization despite its methodological benefits.
Christos Argyropoulos MD, PhD
Miguel Hernan