old but interesting research article [2017]:
Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells
https://pmc.ncbi.nlm.nih.gov/articles/PMC5541866/
"Vertebrate heme synthesis requires three substrates: succinyl-CoA, which regenerates in the tricarboxylic acid cycle, iron and glycine. For each heme molecule synthesized, one atom of iron and eight molecules of glycine are needed."
Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells
Vertebrate heme synthesis requires three substrates: succinyl-CoA, which regenerates in the tricarboxylic acid cycle, iron and glycine. For each heme molecule synthesized, one atom of iron and eight molecules of glycine are needed. Inadequate ...