🧬 How do AlphaFold2 and ESMFold stack up when it comes to functional annotation?

🔗 AlphaFold2 and ESMFold: A large-scale pairwise model comparison of human enzymes upon Pfam functional annotation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.01.008

📚 CSBJ: https://www.csbj.org/

#AlphaFold2 #ESMFold #AIinScience #ProteinStructure #Enzymes #Pfam #UniProt #AlphaFold #HumanProteome #FunctionalAnnotation #AIinBiology #ComputationalBiology #FunctionalGenomics

I see #PFAM has moved to #IntroPro (at EBI) at some point - anyone got the announcement or press release handy? Wikipedia could do with an update... https://en.wikipedia.org/wiki/Pfam

http://pfam.xfam.org/ just says "The Pfam website now serves as a static page with no data updates. All links below redirect to the closest alternative page in the InterPro website." and https://interpro-documentation.readthedocs.io/en/latest/pfam.html doesn't add much.