Guillaume MéricPeople with IBS are more likely to develop #colorectal #cancer, and the role of the #microbiota is unclear. In this study published in #Science a few weeks ago, authors screen bacteria isolated from individuals with #IBS for genotoxic effect & discover a new family of DNA damage-inducing metabolites called indolimines. #Morganella morganii is found to produce it and exacerbates tumours in a mouse CRC model. Neat work!