Victoria Stuart 🇨🇦 🏳️‍⚧️Jul 7, 2023

This, Science magazine 2016, is older (still an incredible achievement) but recent discussion:

Design and synthesis of a minimal bacterial genome
https://www.science.org/doi/10.1126/science.aad6253
Discussion: https://news.ycombinator.com/item?id=36626656

A goal in biology is to understand the molecular and biological function of every gene in a cell. One way to approach this is to build a minimal genome that includes only the genes essential for life. ...

#MolecularGenetics #SyntheticBiology #MinimalGenome #genomics #MolecularFunction

Show threadGene OntologyMar 9, 2023
First of all, some background. Every GO term has several components, including at least:
+ #GOTermName
+ unique #GOTermIdentifier: prefix 'GO:' and 7 digits
+ definition
+ aspect: #CellularComponent, #MolecularFunction, or #BiologicalProcess
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Show threadGene OntologyMar 8, 2023
When a novel #MolecularFunction or #BiologicalProcess is published our network of #biocurators usually find it-but we highly encourage authors/researchers to contact us about their novel research, or even if they find errors/omissions in the #GeneOntology (mistakes happen!) 2/4
Gene OntologyMar 8, 2023
Keanumycins- a great name for a new group of antimicrobial peptides with a punch. But what happens when a brand new #MolecularFunction is discovered? Why, we create a new #GoTerm for it!
1/4
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RT @marklewismd
The perfect drug name doesn't exi--
https://twitter.com/marklewismd/status/1633192556707336192
Mark Lewis on Twitter

“The perfect drug name doesn't exi--”

Twitter
Show threadGene OntologyDec 6, 2022
Use either https://go.princeton.edu/cgi-bin/GOTermFinder or https://www.yeastgenome.org/goTermFinder, choose an aspect (#biologicalprocess, #molecularfunction, or #cellularcomponent), and submit OR modify first by uploading a background list, excluding certain #evidencecodes, or other options.
Generic Gene Ontology Term Finder