Levofloxacin for preventive treatment of Multidrug Resistant Tuberculosis (MDR TB)
Multidrug resistant tuberculosis (MDR TB) affects half a million people each year. ...........
#ClinicalTrial #Levofloxacin #MDR #MDRTB #MultidrugresistantTB #Multidrugresistanttuberculosis #Mycobacteriumtuberculosis #TB #TBCHAMPTrial #Tuberculosis #VQUINtrial
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/levofloxacin-for-preventive-treatment-of-multidrug-resistant-tuberculosis-mdr-tb/

Ok this is alarming:

Emergence of bedaquiline-resistant tuberculosis and of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains with rpoB Ile491Phe mutation not detected by Xpert MTB/RIF in Mozambique: a retrospective observational study

#TB #AMR #antibiotics #bedaquiline #MDRTB #tuberculosis #IDMastodon #infectiousdiseases

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00498-X/fulltext?dgcid=raven_jbs_aip_email

Look at all those acquisitions of #bedaquiline resistance (red dots) after using it (green bars) for treatment of #MDRTB

#TB #tuberculosis #AMR #infectiousdiseases #IDMastodon #medicine #antibiotics

Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00172-6/fulltext?dgcid=raven_jbs_aip_email

Looks like #TPT works for #MDRTB contacts.
#TB #tuberculosis #IDMastodon #infectiousdeseases

Effectiveness and safety of tuberculosis preventive treatment for contacts of multidrug-resistant tuberculosis patients: A systematic review and Meta-analysis - Clinical Microbiology and Infection https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00477-9/fulltext?dgcid=raven_jbs_aip_email

https://www.youtube.com/watch?v=yiflu3nL7Zw

I would like to aim this success at all the injustice in the world right now perpetrated by for profit companies. Collect the data, line everything up, and point them at bringing it to light.

#dftba #mdrtb #xdrtb #bekind

An algorithm might be useful for discovering posts. There. I said it.

If 100 people boosted something between 2:35 and 2:45, but I happened to be not looking at my social media at that time, I still wouldn't know. Seeing posts here is very time-dependant.

However, some sort of algorithm might decide that if 100 people that I follow all boosted this, it sure might be something that I want to see. It would probably be right. No, it shouldn't be mandatory. I think it should be opt-in, probably even require a plug-in on the instance level.

I started thinking about this because even though several people that I follow boosted this, I nearly missed it. And I think this is something that you should see too.

https://dftba.club/@Kamirose/110696654685450121
[email protected] - Johnson & Johnson is poised to kill hundreds of thousands (if not millions) of people with treatable #Tuberculosis by exploiting loopholes in order to extend their monopoly on the drug #Bedaquiline after already having had 20 years of patent protection.

J&J think you won’t care because it’ll mostly be impoverished people in poor countries who will die. Prove them wrong.

https://youtu.be/tMhgw5SW0h4

#JNJ #MDRTB #JohnsonAndJohnsonGreed

UPDATE: https://dftba.club/@Kamirose/110707177144189058

Johnson & Johnson is poised to kill hundreds of thousands (if not millions) of people with treatable #Tuberculosis by exploiting loopholes in order to extend their monopoly on the drug #Bedaquiline after already having had 20 years of patent protection.

J&J think you won’t care because it’ll mostly be impoverished people in poor countries who will die. Prove them wrong.

https://youtu.be/tMhgw5SW0h4

#JNJ #MDRTB #JohnsonAndJohnsonGreed #PatientsNotPatents