And we're ready to go again...

Delighted to announce the 2nd UCL Advances and Innovations in Clinical Infectious Diseases symposium

Focus on research shaping Infectious Diseases practice in next few years

4th June 2024. In person & online. Register 👇https://uclinfectioncourses.wordpress.com/2024-event/ #medicine #IDMastodon #infectiousdeseases #academia #science

One potential explanation for low level #HIV viral load in patients that are otherwise fully compliant with #antiretrovirals / #ARV / #ART

CD4 T cells that persist and reduced CD8 T cell activity. Question is, is this host or viral mediated?
#medicine #MedMastodon #IDMastodon #infectiousdeseases

https://www.nature.com/articles/s41591-023-02611-1

Viral and host mediators of non-suppressible HIV-1 viremia - Nature Medicine

Understanding the heterogeneity of HIV infection, such as in persons with non-suppressible HIV-1 viremia despite adherence to antiretroviral treatment, is crucial to better tailor therapeutic interventions to abrogate HIV-1 persistence.

Nature

Looks like #TPT works for #MDRTB contacts.
#TB #tuberculosis #IDMastodon #infectiousdeseases

Effectiveness and safety of tuberculosis preventive treatment for contacts of multidrug-resistant tuberculosis patients: A systematic review and Meta-analysis - Clinical Microbiology and Infection https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00477-9/fulltext?dgcid=raven_jbs_aip_email

CPE and plasmid transfer in hospitals – what can we do? A rapid reflection from ICPIC 2023

I’ve had the pleasure of a few days in Geneva enjoying some fine Swiss hospitality, and fine science at ICPIC 2023. Here’s rapid reflection on scaling the risks attached to plasmid-mediated transmi…

Reflections on Infection Prevention and Control

Reminder to pick your outcomes.

Vancomycin vs Fidaxomicin in #Cdiff- same mortality, but lower recurrence with fidaxo
#Clostridiumdifficile #antibiotics #microbiology #IDMastodon #infectiousdeseases

The Effect of Antibiotic Therapy for Clostridioides difficile Infection on Mortality and Other Patient-Relevant Outcomes: a Systematic Review and Meta-analysis - Clinical Microbiology and Infection https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00420-2/fulltext

This we really don't want to see.

Increase in #Candidaauris cases in bloodstream.

V v hard to treat. Resistant +++
#AMR #microbiology #mycology @microbiology #IDMastodon #infectiousdeseases @infectiousdiseases

Candida auris rates in blood culture on the rise: results of US surveillance

https://journals.asm.org/doi/10.1128/spectrum.02216-23

The hardest challenge in stewardship remains.... the people (#doctors)!

You provide point-of-care measures of bacterial infection (Biofire & PCT measurements) for patients with respiratory infection, and.... no difference in antibiotic consumption. 🤷

#AMR #AMS #antimicrobialstewardship #microbiology #IDMastodon #infectiousdeseases #medicine #antibiotics #diagnostics #ED #POC

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00359-2/fulltext?dgcid=raven_jbs_aip_email

@DMAronoff totally - i post ID / microbiology / immunology stuff everyday. In fact I've noticed quite a few more medical people here in last few weeks. Now with more shiny apps and websites to access the service too & no ads!
#IDMastodon #medicine #MedMastodon #microbiology #infectiousdeseases