
Healing Belongs at Home – Dr. Charu Dutt Arora’s Powerful TEDx Greenfield Talk - Asian Talks
Among these voices was Dr. Charu Dutt Arora, Consultant Physician in Geriatrics, Palliative Care, and Infectious Diseases at AmeriHealth, Asian Hospital,
Asian Talks
Healing Belongs at Home – Dr. Charu Dutt Arora’s Powerful TEDx Greenfield Talk – Tycoon World
Among these voices was Dr. Charu Dutt Arora, Consultant Physician in Geriatrics, Palliative Care, and Infectious Diseases at AmeriHealth, Asian Hospital,
Tycoon WorldOutcomes of endovascular treatment in nonagenarians with symptomatic peripheral arterial disease
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d10776790e72"> Summary: Background: To report the clinical outcomes of endovascular therapy in nonagenarians
treated for symptomatic peripheral arterial disease (PAD). Patients and methods: This
is a retrospective analysis of 81 nonagenarians (mean age 93±2.4 years) treated by
endovascular therapy for chronic limb threatening ischemia (CLTI) or claudication
between December 2017 and August 2023. The composite of amputation and/or death (amputation-free
survival; AFS) was the primary endpoint. Technical success, mortality, major limb
amputation, risk for Major Adverse Cardio-Cerebro-vascular Events (MACCE) and re-intervention
during follow-up were additionally analysed. Results: Most patients presented with
CLTI (n=75, 93%). Popliteal artery interventions were most frequently performed (n=59,
73%), followed by superficial femoral artery (n=57, 70%), tibial (n=49, 61%), aortoiliac
(n=11, 14%) and common femoral artery (n=7, 9%) procedures. The technical success
rate was 100% and the in-hospital mortality was 1% (n=1). At 24 months the AFS was
23.5%, while the major amputation and mortality rates were 4.9% and 75.3% respectively.
In the same period the rate of MACCE was 74.1% and the freedom from re-intervention
rate amounted to 85.2% The cox regression analysis revealed a lower AFS among males
(HR:1.8, 95% CI: 1.06–3.03, p=0.03) and a higher risk for MACCE in patients on warfarin
(HR:3.1, 95% CI:1.26–7.59, p=0.01). Conclusions: Despite the high technical success
and the low amputation rates, a very high mortality rate at follow up was observed
among nonagenarians undergoing endovascular procedures for PAD. Male gender and Warfarin
administration increased the risk for adverse events.
</p>
ScienceOpen
Could getting rid of old cells turn back the clock on aging?
Researchers are investigating medicines that selectively kill decrepit cells.
Ars Technica