Cracking the functional domains of the RADX gene during replication. 🧬

Jessica Chevallier & Pierre Caron together highlight work from the #CortezLab which is now available online, ahead of print #JMolBiol.

Read the preLight! 👉https://prelights.biologists.com/highlights/crispr-dependent-base-editing-screens-identify-separation-of-function-mutants-of-radx-with-altered-rad51-regulatory-activity/

#CRISPR #GenomeStability #Replication #DSBs

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity - preLights

Cracking the functional domains of the RADX gene during replication

preLights