High-THC cannabis linked to psychosis, addiction: study | Richard J. Baum posted on the topic | LinkedIn

“Cannabis products containing high concentrations of delta-9-tetrahydrocannabinol (THC) -- the main psychoactive compound in marijuana -- were linked to psychosis, schizophrenia, and addiction, a systematic review found. Across 99 studies examining the effects of high-concentration THC products on mental health outcomes, 70% of the nontherapeutic studies (i.e., those not attempting to treat a medical condition or symptom) showed an unfavorable association with psychosis or schizophrenia and 75% found a relationship to cannabis use disorder (CUD). Anxiety and depression appeared to be worsened in 53% and 41% of such studies, respectively, with even higher rates when studying healthy individuals specifically, reported Jonathan M. Samet, MD, of the Colorado School of Public Health in Aurora, and co-authors, writing in the Annals of Internal Medicine.opens in a new tab or window The findings complement those of prior systematic reviewsopens in a new tab or window in "reinforcing the conclusionopens in a new tab or window that higher THC concentrations increase the risk for adverse mental health outcomes, particularly for psychosis or schizophrenia (in both healthy persons and those with preexisting psychosis) and CUD.” #Marijuana #Cannabis #THC