What keeps the TETs in check?

“…this preprint reveals a previously unknown function of OGT in regulating transposable elements and gene expression in mESCs…”

Intrigued? Check out the preLight from Mansi covering work from the #Faulkner_Lab, #AnjanaRaoLab & #SAMyers_lab.

#preLight 👉 https://prelights.biologists.com/highlights/ogt-prevents-dna-demethylation-and-suppresses-the-expression-of-transposable-elements-in-heterochromatin-by-restraining-tet-activity-genome-wide-v2/

#biology #preprint #heterochromatin #genomics #StemCells