We are hiring! SPecifically, a PostDoc for data management and connectomics as part of a large clinical research group. The details can be found here: https://www.linkedin.com/posts/epiconn_open-position-apply-now-the-epiconn-activity-7413211951125688320-Wqi5

Please apply if you are interested in up to four years in Vienna, one of the most liveable cities in the world!

#university #medicaluniversityofvienna
#research #vienna #austria #ismrm #mri #7Tesla #epilepsy #connectomics #data_management

**OPEN POSITION - APPLY NOW** The EPICONN Project is a new interdisciplinary Clinical Research Group combining clinical neuroscience, neuroimaging, and computational modelling to reveal network… | EPICONN

**OPEN POSITION - APPLY NOW** The EPICONN Project is a new interdisciplinary Clinical Research Group combining clinical neuroscience, neuroimaging, and computational modelling to reveal network mechanisms of epilepsy. It will develop cutting-edge machine learning and multi-modal data analytics methods to support clinical decisions for people with epilepsy. It will integrate imaging, EEG, genomics, and clinical data into robust prediction models for disease progression and treatment response. As a central position in EPICONN we are seeking a Postdoctoral Researcher to take a leading role in coordinating patient data-related research workflows and the translation of cutting-edge AI tools into clinical decision making, including multi-modal data integration and management and development of robust data acquisition and management strategies for EPICONN. Your Mission ➡️ Develop, oversee, and implement a project wide data management strategy, process and systems for multi-modal medical data ➡️ Translate research results to clinical tools, integrate research results into robust pipelines and tools that can be used in clinical settings ➡️ Interface closely with the Department of Neurology (DoN) for patient inclusion and study logistics. ➡️ Develop and implement Standard Operating Procedures (SOPs) for data acquisition, transfer, and quality control — with an emphasis on automation and reproducibility. ➡️ Ensure data readiness for multimodal modelling and AI-based analysis within the EPICONN consortium. ➡️ Lead efforts in data stewardship, harmonization, and model validation across imaging, electrophysiological, and behavioural datasets. ➡️ Contribute to the development of multimodal AI models and their preparation for clinical translation. Your Profile 🧠 PhD (or equivalent) in a field of biomedical engineering, computer science, medical informatics, neuroscience, or a related field. 🧠 Proven experience in imaging research or computational neuroscience (e.g., MRI, EEG), medical informatics or data acquisition/evaluation (BIDS standard, Neurodesk, etc.). 🧠 Strong skills in data management tools (e.g., REDCap, DataLad, Neurobagel). 🧠 Experience in Python and/or familiarity with AI / machine learning frameworks is a strong advantage. 🧠 Excellent communication, organizational, and collaborative skills. 🧠 Familiarity with hospital workflows, GCP principles, and research data privacy regulations. We Offer ➡️ A 4-year funded position (1-year trial + 3-year extension) within a cutting-edge interdisciplinary research environment. ➡️ Close collaboration with experts in neurology, medical imaging, AI, and clinical research. ➡️ Access to advanced computational infrastructure and mentorship for career and grant development. ➡️Potential for continued employment in EPICONN Phase 2. How to Apply - send your CV, motivation letter, and contact information for two references (in one PDF) to: [email protected] Application deadline: 20.01.2026

The (extended) ISMRM deadline is over and my team managed to submit 8 abstracts - how did it go for you?

#university #medicaluniversityofvienna
#research #vienna #austria #ismrm #mri #7Tesla

This year's ESMRMB has started in Marseille! Look at this splendid location!

#university #medicaluniversityofvienna
#reseach #vienna #austria #esmrmb #mri #7Tesla

My year abroad has ended and I have returned to Vienna. AN Ideal opportunity to check out my complete podcast series. ;-)

https://creators.spotify.com/pod/profile/gilbert-hangel/episodes/

#MRI #7T #7Tesla #MRSI
#Glioma #research #UCL #medicaluniversityofvienna #FWF

Epic Adventures UK • A podcast on Spotify for Creators

Ein Jahr zur Forschung im United Kingdom - Gilbert Hangel teilt seine Erfahrungen mit der Welt.

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Yesterday, we had a lovely away day of the OxCin physics group down at the river - learning about Spinoff ideas and getting rained on.

#MRI #7T #7Tesla #MRSI #research #Oxford

Yesterday I had the honour to present our 7T MRI in epilepsy research at the Kempenhaeghe annual symposium in the Netherlands.
Thanks for having me!

#mri #7Tesla #epilepsy #medicaluniversityofvienna #kaempenhaeghe #research

Imaging of increased peritumoral glutamate and glutamine in gliomas using 7T MRSI

Abstract Objectives Diffuse gliomas, due to their infiltrative properties, still lack effective treatment options. Recent research indicates that infiltration, malignancy, and symptoms such as epilepsy are related to synaptic connections between infiltrating glioma cells and cytotoxic levels of glutamate release. We previously showed that high-resolution 7T magnetic resonance spectroscopic imaging (MRSI) can resolve metabolic heterogeneities in gliomas. With this study, we evaluated 7T MRSI-derived glutamate (Gln) and glutamine (Glu) ratio maps for their use in defining infiltrative tumor activity in the peritumoral region. Materials and Methods We analyzed 7T MRSI scans of 36 patients with low- and high-grade gliomas. Within the visible tumor and a peritumoral shell, we calculated medians and Dice similarity coefficients (DSC) for nine metabolic ratios with and without hotspot thresholding and evaluated their correlation to and statistical significance between clinical parameters (e.g., tumor-associated epilepsy, IDH status, grade). Results The Glu/tCr (total creatine) median was significantly higher in the peritumoral VOI (1.13) compared to the tumor (0.92) and normal-appearing white matter (NAWM, 0.87), while the Gln/tCr median was highest in the tumor (0.77, vs 0.44 peritumoral and 0.33 in NAWM, all significantly different). Glu/tCho (total choline) was significantly higher in the peritumor as well (3.44 vs 2.23 tumoral and 2.06 in NAWM). Peritumoral DSCs for Glu/tCr and Gln/tCr hotspots were comparable (0.53 to 0.51). Peritumoral Gln/Glu was significantly different between patients with and without tumor-associated epilepsy, and intratumoral (Glu+Gln)/tCr was significantly different between IDH mutation and wildtype. IDH mutation correlated negatively with the intratumoral (Glu+Gln)/tCr median (-0.53) and high grade correlated with intratumoral Glx/tNAA, Glx/tCr, and Gln/tCr medians (0.50/0.53/0.58). Conclusions 7T MRSI can not only map relevant metabolic information in the structurally visible tumor volume, but also detect infiltration in the peritumoral area. Gln and Glu are candidates for the development of presurgical imaging and treatment monitoring. ### Competing Interest Statement Julia Furtner has received honoraria for lectures and consultation from the following for-profit companies: Novartis; Seagen; Sanova; and Servier. Matthias Preusser has received honoraria for lectures, consultation or advisory board participation from the following for-profit companies: Bayer; Bristol-Myers Squibb; Novartis; Gerson Lehrman Group (GLG); CMC Contrast; GlaxoSmithKline; Mundipharma; Roche; BMJ Journals; MedMedia; Astra Zeneca; AbbVie; Lilly; Medahead; Daiichi Sankyo; Sanofi; Merck Sharp & Dohme; Tocagen; Adastra; Gan & Lee Pharmaceuticals; Servier; Miltenyi; Boehringer-Ingelheim; Telix; Medscape; and OncLive. ### Funding Statement This research was funded in whole, or in part, by the Austrian Science Fund (FWF) grants 10.55776/KLI646 and 10.55776/KLI1089. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission. Further funding was received from the City of Vienna Fund for Innovative Interdisciplinary Cancer Research project 23088. The financial support by the Austrian Federal Ministry for Digital and Economic Affairs and the National Foundation for Research, Technology and Development, and the Christian Doppler Research Association, is gratefully acknowledged. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: The Institutional Review Board of the Medical University of Vienna gave ethical approval for this work (study number 1991/2018). I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes Image data produced in the present study are available upon reasonable request to the authors after institutional data clearing house approval. Derived numerical values are included in the supplementary data.

medRxiv
Folge 1 - Vorstellung by Epic Adventures UK

Epic Adventures UK ist ein Podcast über das Leben als Gastforscher im Vereinigten Königreich Großbritannien und Nordirland von Gilbert Hangel. Gilbert forscht seit September 2024 an einem Projekt zur 7 Tesla Magnetresonanztomografie und wird nicht nur erklären was es damit auf sich hat, sondern auch seine Erfahrungen mit der Organisation seines einjährigen Abenteuers teilen. Gefördert von dem Österreichischen Wissenschaftsfonds Projekt 10.55776/J4820 . Aufgenommen und bearbeitet mit Podcastle und Audacity. Feedback und Fragen an: [email protected]

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This weekend, the Department of Neurosurgery celebrated its 60 year anniversary as organisational unit.
I had the honour to present my team's ongoing research projects.

Picture by Philipp Lazen

#university #medicaluniversityofvienna
#reseach #vienna #austria #neurosurgery #mri #7Tesla

This September, my reseach fellowship (FWF Schrödinger stipend funded) in the UK starts. Together with my hosts and collaborators, we will further 7T MRSI.

#MRI #7T #7Tesla #MRSI
#Glioma #research #UCL #medicaluniversityofvienna #FWF