Amelia Cervera 🧬Identification of conserved RNA regulatory switches in living cells using RNA secondary structure ensemble mapping and covariation analysis.
#RNASecondaryStructure #MutationalProfiling #5UTR #Riboswitches #RNAThermometers
Uncovering mRNA sequences that control translation initiation.
Uncovering mRNA sequences that control translation initiation - Nature Reviews Molecular Cell Biology
In this Tools of the Trade article, Abdallah (Gilbert lab) describes the development of direct analysis of ribosome targeting (DART), a tool designed to explore 5' UTR sequences for their potential to efficiently initiate translation.
Gal Haimovich 😷🔬☣🏳️🌈🏳️⚧Interesting
"The 5’UTR of HCoV-OC43 Adopts a Topologically Constrained Structure to Intrinsically Repress Translation"
#5UTR #mRNA #translation #Coronavirus
https://www.jbc.org/article/S0021-9258(23)00160-6/fulltext#.Y-0tbIvJgRY.twitter
This can be useful:
"Learning to Generate 5’ UTR Sequences for Optimized Ribosome Load and Gene Expression"