Tsuki

@tsuki_
51 Followers
109 Following
5.3K Posts
Inquisitive computer science and chemistry student, philomath, versatile, scrupulous, dreamer, geek, sensitive, in pursuit of health & a better world.

CRISPR-Cas9: The gene editing tool changing the world

https://www.labiotech.eu/in-depth/crispr-cas9-review-gene-editing-tool/

CRISPR: The gene editing tool changing the world (2025 update)

CRISPR-Cas9 has changed the world with the promise of making gene editing much easier and faster than before. But what is its real potential?

Labiotech.eu
In the Future All Food Will Be Cooked in a Microwave, and if You Can’t Deal With That Then You Need to Get Out of the Kitchen https://www.colincornaby.me/2025/08/in-the-future-all-food-will-be-cooked-in-a-microwave-and-if-you-cant-deal-with-that-then-you-need-to-get-out-of-the-kitchen/
In the Future All Food Will Be Cooked in a Microwave, and if You Can’t Deal With That Then You Need to Get Out of the Kitchen

Update 8/8/2025 – I wrote this the day before a certain post by a popular developer services company. I’ve seen some comments this is a rebuttal – it wasn’t meant to be! But…

Random Thoughts
Use Hyperopt Optimally With Spark and MLflow to Build Your Best Model

Learn best practices and common pitfalls in model tuning with Hyperopt, ensuring optimal performance for your machine learning models.

Databricks
Read “Kolmogorov’s Pacific Quest and the Birth of the KZ Filter“ by Valeriy Manokhin, PhD, MBA, CQF on Medium: https://valeman.medium.com/kolmogorovs-pacific-quest-and-the-birth-of-the-kz-filter-c587e7c39725
Kolmogorov’s Pacific Quest and the Birth of the KZ Filter

In the early 1980s, Andrey N. Kolmogorov — already a towering figure in mathematics — found himself on a research vessel in the Pacific Ocean, chasing an enigmatic turbulence problem. He had recently…

Medium

"Addressing the Impact of Climate Change on Peace and Security"

https://dppa.un.org/en/addressing-impact-of-climate-change-peace-and-security

Addressing the Impact of Climate Change on Peace and Security | Department of Political and Peacebuilding Affairs

The Secretary-General recognized the findings of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (August 2021) -- that the world is facing unprecedented risks from climate change and that every region is affected – as a “code red for humanity”. Inevitably, given the magnitude of the climate emergency, its cascading effects extend beyond the

The behavior of a high-dimensional dynamical system can, very roughly speaking, be divided into two regimes. The first is what one might call the "effective dynamics" regime, in which the complex, high-dimensional dynamics can be well approximated (in the observables that one particularly cares about, at least) by lower-dimensional effective equations or models that emerge from the more fundamental laws of motion, and are easier to understand and analyze. A classical example is the laws of thermodynamics, which can effectively govern (some of the) macroscopic behavior of a large number of interacting particles, due to mixing effects that greatly simplify the impact of most of the degrees of freedom. Another example from physics is Hooke's law, that asserts that an elastic object, such as a spring, exerts a linear restoring force to push it in the direction of its equilibrium. Similar linear restoring force phenomena can be seen across the sciences (such as climate science, biology, economics, or even political science): not as fundamental laws of nature, but as empirically observable laws that emerge from more fundamental ones. Such effective laws can provide a valuable amount of long-term stability, predictability, and simplification to the dynamical understanding of many real-world complex systems. (1/4)

Bacteria in Polymers Form Cables that Grow into Living Gels - www.caltech.edu

https://www.caltech.edu/about/news/bacteria-in-polymers-form-cables-that-grow-into-living-gels

Bacteria in Polymers Form Cables that Grow into Living Gels

Experiments and modeling reveal the unexpected structure that can be seen in bacteria grown in mucus samples and biofilms.

California Institute of Technology
i love dithering i love fractals i love this thing

RE:
https://mastodon.gamedev.place/users/runevision/statuses/113878384920751648
Rune Skovbo Johansen (@[email protected])

Attached: 1 video New dithering method dropped I call it Surface-Stable Fractal Dithering and I've released it as open source along with this explainer video of how it works. Explainer video: https://www.youtube.com/watch?v=HPqGaIMVuLs Source repository: https://github.com/runevision/Dither3D #gamedev #vfx

Gamedev Mastodon
@tamiel @jaztrophysicist @vbuendiar I can't access either

I’m excited to share my newest blog post, "Don't sure cosine similarity carelessly"

https://p.migdal.pl/blog/2025/01/dont-use-cosine-similarity

We often rely on cosine similarity to compare embeddings—it's like “duct tape” for vector comparisons. But just like duct tape, it can quietly mask deeper problems. Sometimes, embeddings pick up a “wrong kind” of similarity, matching questions to questions instead of questions to answers or getting thrown off by formatting quirks and typos rather than the text's real meaning.

In my post, I discuss what can go wrong with off-the-shelf cosine similarity and share practical alternatives. If you’ve ever wondered why your retrieval system returns oddly matched items or how to refine your embeddings for more meaningful results, this is for you!
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I want to thank Max Salamonowicz and Grzegorz Kossakowski for their feedback after my flash talk at the Warsaw AI Breakfast, Rafał Małanij for inviting me to give a talk at the Python Summit, and for all the curious questions at the conference, and LinkedIn.

#cosineSimilarity #embedding #llm #similarity

Don't use cosine similarity carelessly

Cosine similarity - the duct tape of AI. Convenient but often misused. Let's find out how to use it better.