Aneesh Sathe

@neeshter
95 Followers
520 Following
260 Posts

Now: Drug Discovery- ML GNNs, KGs, Organoids
Previously: Founder and CEO: AI for cancer diagnosis
A decade ago: PhD Biophysics

Data Science, DataViz, RStats
aneeshsathe.com

🧪🧬💻🤖🔬🦠🩺💊

📍San Diego

Websitehttps://aneeshsathe.com/about/
Farcasterhttps://warpcast.com/ars
Bluesky 🦋https://bsky.app/profile/aneeshsathe.com

In which we create Mind Hives

https://aneeshsathe.com/the-octotypic-mind/

Emoji killed irony boy

A good litmus test for the morality of software is asking the developers if they would let their kids use it.

Meta execs: Fuck no!

XMPP devs: Yes, that's why I started this project.

Teleology emerges from exapted entropy.

Every few years my brain tells me that we are the kind of human that smokes a pipe. Unfortunately for my brain the cancer causing thing has been too well proven for me to act on that impulse.

I do own 2 pipes though. If not for science I’d be an amazing Gandalf

If you don't boost the posts we can't have any Fedi!

HOW CAN WE HAVE ANY FEDI IF YOU DON'T BOOST THE POSTS?!?!

🐖🪽

Caution: Culture now descending into Life. Exaptation materialisation imminent.

The End of Identity: AI, Plasticity, and the Divergence Machine

Over the past year, the Contraptions club has been reading through history—from Giordano Bruno and Montaigne to Spinoza, Adam Smith, and Hume. We are now using using Venkatesh Rao's Divergence Machine framework as a lens to make sense of the modern world.For context, Venkat posits that human history operates through massive "world machines". The "modernity machine" was constructed around 1200 and operated…

https://aneeshsathe.com/2026/03/07/the-end-of-identity-ai-plasticity-and-the-divergence-machine/

The End of Identity: AI, Plasticity, and the Divergence Machine

Over the past year, the Contraptions club has been reading through history—from Giordano Bruno and Montaigne to Spinoza, Adam Smith, and Hume. We are now using using Venkatesh Rao’s Divergenc…

Aneesh Sathe

How the Fox with the Long Tail Learned to Play in the Dark Forest

I. Everything is a Balinese Cockfight It was after a police chase and a conspiratorial lie that Clifford Geertz and his wife Hildred were accepted into the social fabric of 1958 Bali. Until then they had been ignored, a treatment reserved for intruders. The police chase was the aftermath of attending a cockfight recorded in Geertz’ essay, Deep Play: Notes on the Balinese Cockfight…

http://aneeshsathe.com/2026/02/06/how-the-fox-with-the-long-tail-learned-to-play-in-the-dark-forest/

How the Fox with the Long Tail Learned to Play in the Dark Forest

I. Everything is a Balinese Cockfight It was after a police chase and a conspiratorial lie that Clifford Geertz and his wife Hildred were accepted into the social fabric of 1958 Bali. Until then th…

Aneesh Sathe
The Kernel and the Ark

I. The Wall and the Infinite It is possible that the history of the modern West hinges on a single, melancholic misreading of Voltaire. When Candide, exhausted by the Lisbon earthquake and the brut…

Aneesh Sathe