Maries van den Broek

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Immunology professor and vice-dean for research at the University of Zurich, mother, theater-lover and rowing-addict.
URLhttps://www.immunology.uzh.ch/en/researchunit/oncology.html
We can’t sufficiently emphasize the importance of fundamental science: https://www.nature.com/articles/d41586-022-04172-8.pdf

How to stop Killers from turning on each other?

Engineering CAR-NK cells with ‘don’t kill me’ ligands circumvents problem of trogocytosis-mediated fratricide.

https://www.nature.com/articles/s41591-022-02003-x

KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape - Nature Medicine

A new dual-chimeric antigen receptor (CAR) system enhances the antitumor activity of CAR natural killer cells and makes them less susceptible to therapeutic resistance in preclinical models.

Nature
@TPVogels Whatever could be wrong when you row?
To all immunologists who don‘t yet know: Check out this great seriers of online talks (also available on demand) - Global ImmunoTalks: https://labs.biology.ucsd.edu/zuniga/global_immunotalks.htm
Zuniga Lab | Division of Biological Sciences

Any questions about MHC molecules? Check out this link: https://ccb.lumc.nl/comic-book-273
Comic book - Cell & Chemical Biology

I‘d love to connect with (tumor-)immunologists.