Here's a cute submission for #MicroscopyMonday ❤️ Shown is a primary cilium from an IMCD3 cell labeled with acetylated alpha-tubulin in red. Smoothened, the GPCR that is activated downstream of Sonic Hedgehog signals, is shown in green. To make the heart, the cilium image was duplicated and flipped using Photoshop. Have a great week!

#TBT to one of my favorite cytoneme videos from the lab! Myosin10 (green) travels to tips of dynamic cytonemes extending from NIH3T3 cells (membrane is shown in magenta). Video from Hall et al, 2021, eLife. Video by @Eric_t_Hall

Testing out the new Leica Stellaris tauSTED in the departmental core. Gazing at the floorplate of an E8.5 🐭 developing neural tube is kind of like looking down into the Grand Canyon. Amirite 😊? Image acquired by postdoc Eric Hall with @alexcarisey

I figured out how to take iPhone pics through a small kaleidoscope I found - so a pretty exciting Friday night 😹

I love #fluorescentfriday ! This is an image of a developing mouse showing expression domains of one of our favorite genes, Sonic Hedgehog (SHH). SHH is a signaling protein that provides instructional cues that drive cell fate determination during developmental tissue patterning. Follow me for posts about cell biology, development, microscopy, lab antics, dogs, and an occasional yoga post. Happy Friday! 🦔

We escaped! The Ogden Lab survived!

Gearing up to do the annual holiday escape room with the lab. If you don’t hear from me again, we didn’t get out.

I think it is time to introduce Buster on this platform. He is a very good boy.

Souvenir from the #ASCBiology meeting from grad student Christina Daly. We do not work with #axolotl but I will accept this sticker because I find them to be very cute 😍