Counting to two: how phages decide between lysis and lysogeny https://www.biorxiv.org/content/10.64898/2026.05.14.725151v1
Cameron Thrash
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Professor, USC Marine and Environmental Biology, microbe hunter. Not a bot. he/him
Copper availability controls niche differentiation between comammox Nitrospira and ammonia-oxidizing bacteria https://academic.oup.com/ismecommun/advance-article/doi/10.1093/ismeco/ycag135/8679972?rss=1
Microbially driven organic carbon cycling at the land−sea interface: Advances and an integrated study framework https://onlinelibrary.wiley.com/doi/10.1002/mlf2.70082
A complete-genome view of phylum Nanobdellota and recurrent Form III RuBisCO transfer between archaea and Patescibacteriota https://www.biorxiv.org/content/10.64898/2026.05.13.725050v1
Metagenomic expansion of Joyebacterota identifies Cavimicrobium, a dominant sulfide-producing lineage in anoxic marine ecosystems https://academic.oup.com/ismecommun/advance-article/doi/10.1093/ismeco/ycag137/8680016?rss=1
Using AI as a teaching partner: enhancing critical thinking and digital literacy in microbiology https://journals.asm.org/doi/10.1128/jmbe.00326-25
End-to-end mapping of membrane transport from chemical structure to microorganisms https://www.biorxiv.org/content/10.64898/2026.05.12.724480v1?rss=1
Coarse-graining metabolic networks via feature learning reveals cross-species growth laws https://www.biorxiv.org/content/10.64898/2026.05.13.725055v1
Cultivation-independent high-quality microbial genome reconstruction from environmental samples with midi-metagenomics https://genome.cshlp.org/content/early/2026/05/14/gr280099124
Cultivation-independent high-quality microbial genome reconstruction from environmental samples with midi-metagenomics
Since the majority of microbial organisms still evade cultivation attempts, genomic insights into many taxa are limited to cultivation-independent approaches. However, current methods of metagenomics and single-cell genome sequencing have individual drawbacks, which can limit the quality as well as completeness of the reconstructed genomes. Current attempts to combine both approaches still use whole genome amplification techniques which are prone to bias. Here, we propose a novel approach for the purpose of genome reconstructions that utilizes the potential of cell sorting for targeted enrichment and depletion of different cell types to create distinct cell fractions with sufficient DNA amounts, circumventing amplification. By distributing sequencing efforts over these fractions as well as the original sample, coassemblies become highly optimized for coabundance variation based binning approaches. "Midi-metagenomics" enables accurate metagenome-assembled genome (MAG) reconstruction from individual sorted samples with higher quality than coassembly and binning of multiple distinct samples and therefore improves analyses of the so-called "microbial dark matter".
Mechanisms of chromosomal DNA replication in Escherichia coli and Bacillus subtilis https://academic.oup.com/femsre/advance-article/doi/10.1093/femsre/fuag021/8678207?rss=1
