Prasad Jallepalli, MD, PhD

459 Followers
410 Following
223 Posts

Prof & Lab Head at Memorial Sloan Kettering Cancer Center https://www.mskcc.org/research/ski/labs/prasad-jallepalli

We use genome engineering, chemical biology, advanced light microscopy, and large-scale phosphoproteomics to investigate the molecular mechanisms underlying cell division, genome integrity, and cancer.

FIRE notes that TPUSA targeted 61 professors in 2021. FIRE doesn’t note that it sponsored a TPUSA “free speech” event in 2017. One of my criticisms of FIRE is that it occasionally has difficulty distinguishing between free speech supporters and people who support speech they agree with.

https://www.thefire.org/news/report-scholars-punished-their-speech-skyrocketed-over-last-three-years

REPORT: Scholars punished for their speech skyrocketed over last three years

A new report from FIRE finds that attempts to punish college and university scholars for their speech skyrocketed over the past two decades, from only four in 2000 to 145 in 2022.

The Foundation for Individual Rights and Expression
What if I told you there is no end point to Elon Musk’s insecurity, emotional brokenness, and spastic egotism

Six years ago today, I was diagnosed with stage 4 cancer, Hodgkin’s lymphoma. After six months of chemotherapy & a month of radiation treatments, here I still am.

The Affordable Care Act paid for the treatments that saved my life. But Republicans are still attacking it.

Student Fed Soc invites Judge.

Shit goes down.

Other Judges boycott students from that School

But only the ones who invited the Judge are likely to apply for clerkships with the boycotters.

Sounds not at all stupid.

#lawtwitter #law

Twitter is removing two-factor authentication via text message from accounts, unless you pay for Twitter Blue. If you have a now-idle or hardly used account, as I do, you should take steps to lock it down, starting with 2FA via an authenticator app. https://techcrunch.com/2023/02/18/how-to-keep-twitter-secure-two-factor/
#Twitter #TwitterMigration
TechCrunch is part of the Yahoo family of brands

I've since left twitter in response to Elon Musk's repeated attacks on public health and his repeated endorsement of medical disinformation. My account is locked and people can no longer see the original thread unless they followed me before I left.

In light of the Times story, I think it's important for people to see the original thread in full. I've therefore made a pdf available here:

http://carlbergstrom.com/publications/pdfs/Bergstrom_twitter_25.pdf

Feel free to cross-post that link to twitter if you still indulge.

As #norovirus ramps up in the US, a couple reminders I personally needed:

- Norovirus is an *asshole*. It can live (and infect people) on surfaces for up to four weeks, and you can shed infectious virus for 72 hrs after symptoms end.

- Hand sanitizer and Lysol wipes don’t kill it. Alcohol doesn’t kill it.

- Soap and water followed by fresh bleach in a freshly made solution or steam cleaning (or hot laundry with oxygen or chlorine bleach) works.

https://www.nytimes.com/2018/11/29/smarter-living/norovirus-prevention-stomach-flu-winter.html?unlocked_article_code=xAItHjTZSvoi0J_orUuG0B4XucKB9XMbJDit79j_hLwGaXT2m36WTWNqztYLGAIlCOaSTYpT2o3kOlspwNJrfuoUItkWAg3hZeQwQHFFba5xi_iQrbifBnZaxQUaflQczg1e--2vnfYBVdUKn9YtQn9V-iddCPmV6gVUAMXaVHQGkMiMij8KmviCzO1fqPOmZhXx3hjR3cTjDuSsIvOnL5ZqT7sZ3FoQ71CHk0StB49KIfB5i0F3vgzYqpv_j1hJ2xLfHJssdB9MdZ7uJfkpGOdLbecBpuTiExk8mWlV5idZgkYe6KQzuvsgTfFui4NX8jRLF8m6NZPZLbnbM55980lyDcYZRU74vlL13ynsWKXuKFUILASeFw&smid=share-url 🎁 link

How to Prevent Nasty Stomach Bugs This Winter? More Bleach.

It can survive on surfaces for days, is tricky to kill, and is the source of most stomach bugs in America. It’s norovirus, and we’re headed into prime season. Here’s how to beat it.

The New York Times
Bird flu 'spills over' to otters and foxes in UK

Scientists will monitor the virus, but UK health chiefs say the risk to the public is very low.

BBC News
I'll admit to being skeptical about "synthetic biology", wondering if it's just buzz words, but this recent paper from Daniels et al. blew me away with its combination of novel insights into cell signaling circuitry & its clinical potential #ScienceSunday 1/n
https://pubmed.ncbi.nlm.nih.gov/36480602/
Decoding CAR T cell phenotype using combinatorial signaling motif libraries and machine learning - PubMed

Chimeric antigen receptor (CAR) costimulatory domains derived from native immune receptors steer the phenotypic output of therapeutic T cells. We constructed a library of CARs containing ~2300 synthetic costimulatory domains, built from combinations of 13 signaling motifs. These CARs promoted divers …

PubMed

RT @samueloakford
Elon Musk fired Twitter's entire staff in Brazil except a few salespeople.

Among those fired: "eight people who moderated content on the platform in order to catch posts that broke its rules against incitement to violence and misinformation."

https://www.washingtonpost.com/technology/2023/01/08/brazil-bolsanaro-twitter-facebook/

Come to the ‘war cry party’: How social media helped drive mayhem in Brazil

Just like with Donald Trump's defeat in 2020, supporters of Jair Bolsanaro used social media, particularly Facebook, Twitter and Instagram, to fuel the anger that exploded on Sunday in Brasília.

The Washington Post