Francesco Strozzi

@[email protected]
31 Followers
52 Following
32 Posts
Bioinformatician working on human health, biotechnology, data science and (meta)genomics.
I’m an elder millennial from Italy, living in Paris and passionate about science, food, CrossFit, weightlifting, calisthenics.
LinkedInhttps://www.linkedin.com/in/francescostrozzi
GitHubhttps://github.com/fstrozzi
ORCIDhttps://orcid.org/0000-0002-6845-6982
Show threadFrancesco StrozziNov 9, 2022

Fast forward multiple years and now at #BioTechX several big pharmas are using graph technologies to model data and provide targets insights.

Spoiler alert : I didn’t have the job and of course that company is not among those using this approach now :)

Francesco StrozziNov 9, 2022
Years ago I was interviewing with a big pharma company. Discussing how to facilitate target discovery/validation my suggestion was to use graph databases and ontologies to model data and extract insights. It was dismissed has being “just data curation and not very interesting”
Francesco StrozziNov 9, 2022
Ewan BirneyNov 9, 2022

RT @[email protected]

France just legislated that every parking lot for 80 cars or more must be covered by solar panels

That’s 11GW of new solar (same as 10 new nuclear reactors) powering millions of home - zero new land needed

Climate action is happening, just not at #COP27

https://www.publicsenat.fr/article/parlementaire/l-obligation-de-pose-de-panneaux-photovoltaiques-sur-les-grands-parkings

🐦🔗: https://twitter.com/AssaadRazzouk/status/1590255454088593408

L’obligation de pose de panneaux photovoltaïques sur les grands parkings extérieurs adoptée au Sénat

Les sénateurs ont adopté ce 4 novembre l’article 11 du projet de loi sur l’accélération des énergies renouvelables, qui impose un équipement en ombrières photovoltaïques pour les parkings extérieurs de plus de 80 places.

Public Senat
Francesco StrozziNov 9, 2022
John ConwayNov 8, 2022
Every #Mastodon admin right now.
Francesco StrozziNov 9, 2022
Phil EwelsNov 9, 2022

This has been a long time coming! We've released a DSL2 version of the @nf_core methylseq pipeline. Massive thank you to all the other contributors, especially Patrick Hüther, @njspix and @E_Miller88 . Follow-on releases soon as we start adding new functionality 🚀
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RT @nf_core
Pipeline release! nf-core/methylseq v2.0.0 (Methylation (Bisulfite-Sequencing) analysis pipeline using Bismark or bwa-meth + MethylDackel)

See the changelog: htt…
https://twitter.com/nf_core/status/1590287579240357888

nf-core on Twitter

“Pipeline release! nf-core/methylseq v2.0.0 (Methylation (Bisulfite-Sequencing) analysis pipeline using Bismark or bwa-meth + MethylDackel) See the changelog: https://t.co/fpmprR0UQf”

Twitter
Francesco StrozziNov 9, 2022
Beautiful handmade wrap up for the round table on Accelerating Pharmaceutical Research and the Role of Digital Technologies #BiotechX #CloudComputing #DrugDiscovery
Francesco StrozziNov 9, 2022
Pierre LindenbaumNov 9, 2022
Greta Thunberg on mastodon [email protected] #climatechange
Francesco StrozziNov 8, 2022
Joseph GuhlinNov 7, 2022

Building an aggregator for #ScienceMastodon. Let's you view multiple servers at once. Creating a list of all the science servers I know of. Please let me know of any others!

genomic.social
ecoevo.social
mstdn.science
fediscience.org
scicomm.xyz
scholar.social?

Any others?

Francesco StrozziNov 8, 2022
C. Chase BoltNov 8, 2022

I want to share this recent review of #enhancer function. It’s very well written with a brief and clear focus on each topic. It’s delightful.

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02322-1

Mechanisms of enhancer action: the known and the unknown - Genome Biology

Differential gene expression mechanisms ensure cellular differentiation and plasticity to shape ontogenetic and phylogenetic diversity of cell types. A key regulator of differential gene expression programs are the enhancers, the gene-distal cis-regulatory sequences that govern spatiotemporal and quantitative expression dynamics of target genes. Enhancers are widely believed to physically contact the target promoters to effect transcriptional activation. However, our understanding of the full complement of regulatory proteins and the definitive mechanics of enhancer action is incomplete. Here, we review recent findings to present some emerging concepts on enhancer action and also outline a set of outstanding questions.

BioMed Central
Francesco StrozziNov 8, 2022
James Fellows YatesNov 8, 2022
#BoM Confirmation post to be listed on: https://emiller88.github.io/Mastodon-Bioinformatics/ :)
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