Mastodawn

Broken Pen Apr 23, 2023

[ h o n o r ]Apr 22, 2023

my essay rework of 'should data expire?' is now available to view as part of sun thinking, an exhibition hosted on solar protocol!

link: http://solarprotocol.net/sunthinking/

Solar Protocol

A naturally intelligent network programmed by the sun.

Broken Pen Apr 16, 2023

Vicky van der Togt Apr 14, 2023

A mechanism for #LongCovid

I am beyond excited to finally be able to share what I’ve been working on for the past year.

At the beginning of March 22, I discovered a potential mechanism for #LongCovid. It was a unifying mechanism that could explain every single symptom that patients were reporting, something I never thought possible for a disease that has over 200. Yet, this mechanism actually did.

Link: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1150105/full

Hypothesis: inflammatory acid-base disruption underpins Long Covid

The mechanism of Long Covid (Post-Acute Sequelae of COVID-19; PASC) is currently unknown, with no validated diagnostics or therapeutics. SARS-CoV-2 can cause disseminated infections that result in multi-system tissue damage, dysregulated inflammation, and cellular metabolic disruptions. The tissue damage and inflammation has been shown to impair microvascular circulation, resulting in hypoxia, which coupled with virally-induced metabolic reprogramming, increases cellular anaerobic respiration. Both acute and PASC patients show systemic dysregulation of multiple markers of the acid-base balance. Based on these data, we hypothesize that the shift to anaerobic respiration causes an acid-base disruption that can affect every organ system and underpins the symptoms of PASC. This hypothesis can be tested by longitudinally evaluating acid-base markers in PASC patients and controls over the course of a month. If our hypothesis is correct, this could have significant implications for our understanding of PASC and our ability to develop effective diagnostic and therapeutic approaches.

Frontiers

Broken Pen Apr 14, 2023

Show thread

C_Chell Apr 13, 2023

@cult On Equestria.Social, it's 640 active users.
Before Elon Musk it was around 5 to 10 including the bots.

Broken Pen Feb 7, 2023

The Deer Whisperer 🦌⚓Jan 28, 2023

Tahoma (Mt Rainier) casts a shadow across the early morning sky, as seen from Bonney Lake, Washington:

#Photography #MtRainier #WashingtonState

Broken Pen Jan 20, 2023

SwiftOnSecurity Jan 20, 2023

Broken Pen Jan 20, 2023

Erik McClure Jan 19, 2023

Programmers play coding games not to escape from work, but to live the fantasy of doing any.

Broken Pen Dec 22, 2022

ShivalWolf Dec 22, 2022

This pic is sooo Epicly adorable https://derpibooru.org/3011468

#3011468 - safe, artist:ryanmandraws, princess luna, alicorn, pony, :p, blushing, bust, christmas, clothes, cute, earmuffs, ethereal mane, female, holiday, lunabetes, mare, mlem, portrait, scarf, silly, snow, snowfall, snowflake, solo, solo female, tongue out, winter - Derpibooru

#3011468 - safe, artist:ryanmandraws, princess luna, alicorn, pony, :p, blushing, bust, christmas, clothes, cute, earmuffs, ethereal mane, female, holiday, lunabetes, mare, mlem, portrait, scarf, silly, snow, snowfall, snowflake, solo, solo female, tongue out, winter - Derpibooru

Broken Pen Dec 22, 2022

Dare Obasanjo Dec 22, 2022

I can’t get over $TSLA losing over half its value in 3 months because of its CEO’s side hustle to buy Twitter.

There’s been no material negative news about the company. Just a realization that his reputation is overhyped and investors are now fleeing.

The stock market is vibes.

Broken Pen Dec 18, 2022

Myles McCormack Dec 18, 2022

Whelp, decided to bite the bullet and join Mastodon. Fuck Elon.

Broken Pen Dec 18, 2022

LordBurns Dec 18, 2022

Art Blog	https://broken-pen-draws.tumblr.com/tagged/Drawn%20Post
Cohost	https://cohost.org/broken-pen
Discord	Broken Pen#1077
Horse	yes