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Let me tell you, I've seen more than my fair share of surgery videos involving "de-sheathing" in my research: I don't envy your editing work - but I envy your stomach ;-) But thanks for your reply, the community here can be great at times!
Thanks for your thoughtful comment! You're right - Biodesign can be used in Plaque Incision and Grafting (PIG) for Peyronies. Unfortunately PIG IMHO has (in some studies I have read) a 50/50 chance of erectile dysfunction, nerve injury, instability and so on. In essence, PIG might be rolling the dice to make a bad situation completely untenable. But again, I do thank you for your comment!
A cure for Peronies which is non invasive, works on chronic/non-chronics is worth countless billions.
@ aol... so retro ;-) - sent you an email.
I had to google your condition to empathize, but wow - terrible. I'm truly happy for you that you could solve it! Thanks for your best wishes!
I live in the EU at present, I haven't heard of Dr C. I've seen a little Doctor Worship on Reddit, but no doctor who can deal with Chronic conditions. In the NL the only option was Tunica albuginea plication (TAP) which results in a loss of length. I've read that PIG in 44% of cases fixes this, however... ugh... surgery. From the bottom of my heart I wish you success in this, and I'd love to stay in contact and hear of your recovery - but how on HN?

You are right on the mark. What triggered me was the slide in Sid's presentation: "Assessing Fibroblast Content of Tumor". Peyronie's is all about Fibroblasts. I actually typed my reply quite a few times, deleting mention of Peyronies and retyping it. It's a shameful condition for me, and I realize that I have to get over this. Peyronie's affects 1% to 20% of men, primarily because it's (if you're anything like me) - is impossible to talk about.

Again, you're completely right. Talking about the disease is the first step.

Thanks for your comment. I'm aware of Xiaflex, and it's been clinically proven to work against early-stage Peyronies. When the disease has reached the chronic phase (and calcified) - Xiaflex hasn't been clinically proven. Xiaflex is now on-label for treating Peyronies.

My mistake wasn't acting earlier, because I had no idea what was happening. But thank you again for your comment. Thank you!

This is the most supremely motivating post I've seen in a long time. I know what it is to be diagnosed with cancer, being rushed to surgery - it's amazing how quickly the medical-industrial complex can move once you've got a diagnosis (at least in Australia). I had a short period of contemplating terminally, because cancer claimed the life of most of my family. Thankfully, after surgery it was gone.

To see Sid use his motivation and resources to solve his own problem is the core message (IMHO) of the hacker community.

It makes me look at my own problem (Peyronies) in a different light; a disease which has affected my life in ways which cannot be overstated. Yet, all the money in the world right now can't fix Peyronies - yet in reading his journey my mind has been changed about this.

His slide title: "I'll talk to anyone, I'll go anywhere, and I can be there anytime" is certainly the mindset!

Thanks for posting this - I'm inspired to take similar action for Peyronie's. Anything is possible.

> Doesn't this mean that solar/wind are insanely lucrative?

I used to work in wind energy in the Netherlands, it is only profitable there due to government subsidies. It was/is an enormously complicated system to understand on the whole. I was on the environmental impact side (visualizations) during the permitting process. It's high-risk & enormously expensive during the permitting process (i.e. getting permission to build the wind farm), and beyond that I understand it's a bidding process and again, super complicated on the energy trading side once you're operating. My experience was that the wind farm operators seemed to be doing well financially, but insanely lucrative? I'm not sure about that vs. non-renewables. Everyone I worked with (including myself) believed in green energy as a part of a larger mission to make the world a slightly better place. EU directives on renewables is what pushed the mission forward; the dutch on the whole (surprisingly), do not love wind turbines in their back yard.