I can't believe I haven't seen FUNRICH before! It's awesome! especially it's link to vescilpedia!! The is some ev data we acquired over the weekend http://www.funrich.org/

Happy holidays !!

Trigger warning: This arrived in the mail today : was supposed to be samples in eppendorf tubes :( . Sigh ... Proteomics is hard enough with samples in intact tubes.

What's the oldest poster hanging in your lab? Mine is going on 14 years old

Let’s see I get a notification on twitter/x from my city about the bomb threats to my kids school yesterday . This is the reply I see over there. Makes me glad I’m done with X/twitter .

Sweet ! This 585k dollar low income condo in Davis cut its sale price by 250 dollars ! Now it’s totally affordable!!

Man the king fisher mag bead protocols use a lot of plastic ! I’m thinking of buying a plate washer or just put the plates in a bucket and swish them around . That should work right ? I mean my mass specs are sensitive , but they are not THAT sensitive !

Testing our “new” Parallel automated homogenization & digestion apparatus here at UC Davis . Now I just need a catchy acronym and that nature methods paper will almost write itself !

I usually don't do this, but this is such bull shit. Their instrument may work, but telling people that it will tell them what their western blot binding is utter crap. Seriously, write an actual app note that actually does this, and not just an ingel digest of a purified protein, and I'll be impressed.

This is from the SP4 paper https://pubs.acs.org/doi/10.1021/acs.analchem.1c04200 , which is really good btw . When ever I see optimization steps like this, it just screams to me that this is very hard to reproduce across labs/people. I generally think it's a good trade to trade sensitivity for reproducibility in most cases which I why I like using the King Fisher and Magnetic beads over doing it by hand