@siderea in genetics speak, a mutation can be gain of function or loss of function. Loss of function is also just what it sounds like, a mutation that reduces or eliminates the function of a gene. Since this mutation results in reduced expression of a transcriptional target, they're emphasizing here that the reduced transcription is actually due to a gain of function in a transcriptional regulator
Why did nobody tell me that Curious Zelda is on Mastodon? Y'all need to stop telling people to learn to gain sustenance from air and focus on the important stuff.
My gf is a tennis super fan and she's been complaining about the terrible #usopen highlight reels. Turns out the highlights are AI-selected now and they seem to be just kinda random points. Fun how everything just keeps getting worse and worse.
I've been looking at condos to buy lately, and trying to hold the competing ideas of "what will be the resale on this in 10 years" and "in 10 years global warming will probably have killed me" is giving me serious cognitive dissonance