@alxsim absolument! Oui. Je l ai fait (sections 21/27/29)
| Keywords | Capsule, HGT, phages |
| Position | Research associate @ Institut Pasteur & CNRS |
Olaya Rendueles
- 99 Followers
- 61 Following
- 25 Posts
Microbiologist interested in ecology & evolution
Hi everyone,
We're looking forward to Session 4 of #KlebClub2023 on 25th April 9AM EST next week!
We will have a keynote from @jrpenades, followed by research talks by @wenwenlow from
@imperialcollege @NUSingapore, Nathalie Chen from @PittTweet
We're looking forward to Session 4 of #KlebClub2023 on 25th April 9AM EST next week!
We will have a keynote from @jrpenades, followed by research talks by @wenwenlow from
@imperialcollege @NUSingapore, Nathalie Chen from @PittTweet
Happy monday friends!😀
Join us this week at Session 3 of #KlebClub2023
This tuesday, we'll have a keynote from @DariaVanTyne from @PittTweet, and research talks by @BettinaCheung from @NorthwesternU and Xueting Huang from Tsinghua U.
Register for free: https://sites.google.com/view/klebclub/home
Session 2 of #KlebClub will be airing in less than 24h!
Keynote from Richard Strugnell followed by research talks by Anirudh Desikahn and Ben Yezina .
Register for FREE (link in the picture below)
(Make sure you noticed the hour!)
Akos T KovacsRT @AlvSanMillan
New preprint from the lab! Ever wondered how successful associations between plasmids and bacteria emerge? Work led by the amazing @AidaAdelValle and @LauraToribioC with great collaborators, Carles Ubeda @RafaMCanton @epcrocha and @penamiller
https://www.biorxiv.org/content/10.1101/2023.04.03.535338v1
New preprint from the lab! Ever wondered how successful associations between plasmids and bacteria emerge? Work led by the amazing @AidaAdelValle and @LauraToribioC with great collaborators, Carles Ubeda @RafaMCanton @epcrocha and @penamiller
https://www.biorxiv.org/content/10.1101/2023.04.03.535338v1
Christian KostRT @SchiestlFlorian
A PostDoc position in Chemical Ecology is available in my lab, see https://t.uzh.ch/1sO
Please re-tweet to anyone potentially interested in the job!
A PostDoc position in Chemical Ecology is available in my lab, see https://t.uzh.ch/1sO
Please re-tweet to anyone potentially interested in the job!
Join us today for Session 1 of the Klebsiella Seminar Series (April 4th 9AM EST)! We are looking forward to awesome #Klebsiella Science in a few hours..
Still time to register
New publication from the lab!
We coevolved a phage-producing + phage-sensitive strain and tested the different phage resistance mechanisms, their emergence and their dynamics.
Unexpectedly, new lysogens are unstable and undergo excessive death rate during expo growth.
Other mechanisms of resistance like receptor (capsule) loss are fitter in short evolution times, but later, clones with receptor modifications or displaying phenotypic resistance are fitter.
https://doi.org/10.7554/eLife.83479
We coevolved a phage-producing + phage-sensitive strain and tested the different phage resistance mechanisms, their emergence and their dynamics.
Unexpectedly, new lysogens are unstable and undergo excessive death rate during expo growth.
Other mechanisms of resistance like receptor (capsule) loss are fitter in short evolution times, but later, clones with receptor modifications or displaying phenotypic resistance are fitter.
https://doi.org/10.7554/eLife.83479
We speculate that when the capsule is added (exogenously) to a culture, it can bind antimicrobial peptides (AMPs).
Such sequestration titers AMPs in the media, effectively diluting it & ⤴️⤴️ tolerance, as more compound is required to obtain the same killing effect.
But when the capsule is bound to the cell surface (native form), it facilitates the entry of the AMPs as it retains AMPs near the cell surface where it can easily bind to the LPS, & ⤴️⤴️ susceptibility.