Nicole Rust

@NicoleCRust@neuromatch.social
4.5K Followers
762 Following
3.7K Posts
Professor (UPenn). Brain researcher. Science advocate. Book: Elusive Cures (Spring 2025). https://press.princeton.edu/books/hardcover/9780691243054/elusive-cures
https://nicolecrust.com/

Wonderful to chat with Paul on Brain Inspired, where we discuss many things. Among them: What are we brain researchers trying to do here (wrt causality)? I also stick my neck out to predict the next big breakthrough in emotion research.

0:00 – Intro
6:12 – Nicole’s path
19:25 – The grand plan
25:18 – Robustness and fragility
39:15 – Mood
49:25 – Model everything!
56:26 – Epistemic iteration
1:06:50 – Can we standardize mood?
1:10:36 – Perspective neuroscience
1:20:12 – William Wimsatt
1:25:40 – Consciousness

Thanks for having me!

https://braininspired.co/podcast/214/

Wonderful to chat with Paul on Brain Inspired, where we discuss many things. Among them: What are we brain researchers trying to do here (wrt causality)? I also stick my neck out to predict the next big breakthrough in emotion research.

0:00 – Intro
6:12 – Nicole’s path
19:25 – The grand plan
25:18 – Robustness and fragility
39:15 – Mood
49:25 – Model everything!
56:26 – Epistemic iteration
1:06:50 – Can we standardize mood?
1:10:36 – Perspective neuroscience
1:20:12 – William Wimsatt
1:25:40 – Consciousness

Thanks for having me!

https://braininspired.co/podcast/214/

@xkcdbot
Timely.

title text: If you think curiosity without rigor is bad, you should see rigor without curiosity.

(https://xkcd.com/3101)
(https://www.explainxkcd.com/wiki/index.php/3101)

Thank you, @thetransmitter

In this excerpt, I fast forward to the end of Elusive Cures to explain why I am so unequivocally optimistic about the next steps for brain research.

For those of you who (like me) like to listen, I've narrated this clip (~10 min). The text is there too.

In her new book, published today, neuroscientist @NicoleCRust takes a bird's-eye view of where the neuroscience community is currently and where it needs to go to solve some of the field’s biggest questions.

https://www.thetransmitter.org/community/elusive-cures-why-neuroscience-hasnt-solved-brain-disorders-and-how-we-can-change-that-an-excerpt/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20250610-elusive-cures

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt

In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community's "Grand Plan."

The Transmitter: Neuroscience News and Perspectives

@EVDHmn @princetonupress

Oh, wow @EVDHmn - thank you so much for these kind and generous words. I'm touched and flattered.

It's publication day for 📘Elusive Cures. What a moment!

This is my 1st book & my 1st time on Mindscape (one of my favorite podcasts).

Here, @seanmcarroll and I have a wide-ranging conversation about the brain, including: Why are brain and mental disorders so hard to understand and treat?

The podcast: https://www.preposterousuniverse.com/podcast/2025/06/09/317-nicole-rust-on-why-neuroscience-hasnt-solved-brain-disorders/

The book: https://press.princeton.edu/books/hardcover/9780691243054/elusive-cures

@jonny
Oh no! I’m so sorry.

My new piece in Nature Human Behavior: "We need to fight for the next generation of US researchers"

All trainees need 3 things to thrive. In the US, those things have been ripped away. Let's brainstorm and fight to get them back.

(share link): https://www.nature.com/articles/s41562-025-02246-x.epdf?sharing_token=hcXev4a-31TU_a-OJK6ZMtRgN0jAjWel9jnR3ZoTv0MYALIXurixdPyNhiHwMhlzGSYzTbCgk8k-LvtRgSz04GX7xmjDu30cxJslQ-hufZZA8Li3FllJdSC3Le0yVRFBhJDn4VkC9QTpwrJeB0iXHDc0lY-LY-dngmlCZxfZYjE%3D