Matrix Science will be attending BSPR2026 in Cambridge, UK, on 13-15 July. Come chat with us about the latest developments with Mascot. Abstract and early bird registration deadline is 15 May, so it's best to book your place soon!

https://www.bspr.org/annual-meetings

#proteomics #massspec

You can now use large language model (LLM) coding assistants to interact with Mascot Server. This includes anything that can be programmed with the LLM, from simple automation tasks to complex mining and merging of results.

https://www.matrixscience.com/blog/automate-data-processing-and-reporting-with-coding-assistants.html

#proteomics #MassSpec

Mascot Newsletter, April 2026:

Mycobacteria spectral libraries.

Orthogonal translation systems for lysine aminoacylation.

Matrix Science at ASMS 2026.

https://www.matrixscience.com/nl/202604/newsletter.html

#proteomics #massspec

Mascot Newsletter, March 2026:

Search BLIB spectral libraries with Mascot.

PET hydrolase expressed in fruit flies.

UK office has moved.

https://www.matrixscience.com/nl/202603/newsletter.html

#proteomics #massspec

matrixscience.com is being overwhelmed by millions of HTTP requests from distributed botnets, essentially a distributed denial of service (DDoS) attack. We are forced to mitigate it by restricting access to certain pages of dynamic content.

https://www.matrixscience.com/whats_new/mitigations-against-uncontrolled-web-crawlers-and-bots.html

#proteomics #massspec

Thunder-DDA-PASEF is an acquisition strategy for capturing more human leukocyte antigen (HLA) class I peptide ligands on Bruker timsTOF instruments. This month's blog shows how you can process Thunder-DDA-PASEF data with Mascot Distiller.

https://www.matrixscience.com/blog/processing-thunder-dda-pasef-data-with-mascot-distiller.html

#proteomics #massspec

Using the blib2msp converter, Mascot Server can now search DDA spectral libraries in BLIB format. Here's an example for identifying mycobacteria.

https://www.matrixscience.com/blog/identifying-mycobacteria-with-custom-spectral-libraries.html

#proteomics #massspec

The UK office of Matrix Science Ltd has moved one block up the road. New address: 83 Baker Street, London W1U 6AG, UK. There is no other change to bank details or email addresses.

https://www.matrixscience.com/whats_new/change-of-address-for-uk-office.html

Mascot Newsletter, February 2026:

Strange software errors? Check your disk space.

Proteomic signatures in human fingertip regeneration.

Customise columns in the search log.

https://www.matrixscience.com/nl/202602/newsletter.html

#proteomics #massspec

Mascot Server can create and search NIST MSP formatted spectral libraries but not BLIB -- until now! We have developed an MSP to BLIB to MSP converter that allows Mascot Server to use BLIB libraries.

https://www.matrixscience.com/blog/converting-blib-spectral-libraries-to-msp-and-back-again-for-use-with-mascot-server.html

#proteomics #massspec