We've compiled a new skill for coding assistants that helps you write custom quantitation reports for Mascot Distiller. An example script for exporting results into MSstats is included.

https://www.matrixscience.com/blog/automation-of-report-creation-for-mascot-distiller-msstats-report.html

#proteomics #massspec

It was a pleasure to meet many of you at ASMS 2026 in San Diego, CA this June. We presented three posters featuring Mascot DIA using real data. PDF copies of the posters: https://www.matrixscience.com/asms_2026.html

#proteomics #massspec

Mascot Newsletter, May 2026:

We're presenting three DIA posters at ASMS 2026.

Oleuropein-based olive leaf extract with cardiovascular exercise.

Upcoming conferences: BSPR 2026 and IMSC 2026.

https://www.matrixscience.com/nl/202605/newsletter.html

#proteomics #massspec

Matrix Science will be attending BSPR2026 in Cambridge, UK, on 13-15 July. Come chat with us about the latest developments with Mascot. Abstract and early bird registration deadline is 15 May, so it's best to book your place soon!

https://www.bspr.org/annual-meetings

#proteomics #massspec

You can now use large language model (LLM) coding assistants to interact with Mascot Server. This includes anything that can be programmed with the LLM, from simple automation tasks to complex mining and merging of results.

https://www.matrixscience.com/blog/automate-data-processing-and-reporting-with-coding-assistants.html

#proteomics #MassSpec

Mascot Newsletter, April 2026:

Mycobacteria spectral libraries.

Orthogonal translation systems for lysine aminoacylation.

Matrix Science at ASMS 2026.

https://www.matrixscience.com/nl/202604/newsletter.html

#proteomics #massspec

Mascot Newsletter, March 2026:

Search BLIB spectral libraries with Mascot.

PET hydrolase expressed in fruit flies.

UK office has moved.

https://www.matrixscience.com/nl/202603/newsletter.html

#proteomics #massspec

matrixscience.com is being overwhelmed by millions of HTTP requests from distributed botnets, essentially a distributed denial of service (DDoS) attack. We are forced to mitigate it by restricting access to certain pages of dynamic content.

https://www.matrixscience.com/whats_new/mitigations-against-uncontrolled-web-crawlers-and-bots.html

#proteomics #massspec

Thunder-DDA-PASEF is an acquisition strategy for capturing more human leukocyte antigen (HLA) class I peptide ligands on Bruker timsTOF instruments. This month's blog shows how you can process Thunder-DDA-PASEF data with Mascot Distiller.

https://www.matrixscience.com/blog/processing-thunder-dda-pasef-data-with-mascot-distiller.html

#proteomics #massspec

Using the blib2msp converter, Mascot Server can now search DDA spectral libraries in BLIB format. Here's an example for identifying mycobacteria.

https://www.matrixscience.com/blog/identifying-mycobacteria-with-custom-spectral-libraries.html

#proteomics #massspec