Maitreya Dunham

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210 Posts
My lab works on genome evolution, using yeast genetics, experimental evolution, and comparative genomics. Chair, Department of Genome Sciences at University of Washington.
websitehttps://depts.washington.edu/dunhamlab/
Blueskyhttps://bsky.app/profile/maitreya.bsky.social
@MCDuncanLab Plasmidsaurus is doing yeast genomes for $150. Could do it bulk segregant style where you pool a bunch of segregants with and without the band and then it's just 2 genomes worth of sequencing. Anyway, now I'm curious!
@MCDuncanLab whoa! You have to map it!
Nothing like new data to lift the spirits. 44 new caspofungin-resistant yEvo genomes! Can't wait to get these back in the hands of the high school students who evolved these yeast strains.
Genome Sciences is looking for a Grants Manager for the Model Organism Genetics labs (which include me!): https://uwhires.admin.washington.edu/ENG/candidates/default.cfm?szCategory=jobprofile&jobhistory=1&szOrderID=242737
UW Human Resources

University of Washington Human Resources

New work in Genetics by Renee Geck when she was in my lab, Nick Powell, et al. delving into novel variants in G6PD in the All of Us resource. Functional analysis of G6PD variants associated with low G6PD activity in the All of Us Research Program https://academic.oup.com/genetics/article/228/4/iyae170/7912375
Had a great workshop yesterday with the Hutch SEP & a bunch of local teachers interested in using our Yeast Madness kit in their classes. This module uses strains evolved by previous yEvo high school students and teaches about mutations, fitness, & cell biology. https://www.fredhutch.org/en/education-training/teachers/science-education-partnership/sep-curriculum/yevo-lab.html
Here's the paper, which is still one of my favorites. High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast https://genome.cshlp.org/cgi/content/long/23/4/698
High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast

An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms

Well how nice is this interview with @blake_billmyre about the impact on him of a talk I gave about Ivan Liachko's ARS genomics project! That was a pretty fun conference :) mSphere of Influence: When a sequencer is more than a sequencer | mSphere https://journals.asm.org/doi/full/10.1128/msphere.00433-24
The department surprised me with a very nice "new chair" toast at the retreat and gave me a literal UW camping chair as a gift 🥹