Single cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation https://doi.org/10.7554/eLife.77663.
Delighted to share out latest data! Brilliant work by @[email protected] and all the team.
🐦🔗: https://twitter.com/p_saunder/status/1603813501092261888
Today @[email protected] etal. present in @[email protected] a library of base editors #MitoKO to ablate all protein-coding genes in mouse mtDNA. #MitoKO will help generating new, clinically meaningful models for mechanistic, drug discovery and pre-clinical studies https://www.nature.com/articles/s41551-022-00968-1 1/8
🐦🔗: https://twitter.com/mito_gene/status/1599745497627267072
A library of double-stranded-DNA deaminase-derived cytosine base editors allows for the precise ablation of every mtDNA protein-coding gene in the mouse mitochondrial genome.
Today we’re sharing a deep-learning method for protein design called RoseTTAFold Diffusion. With minimal input, it turns prompts (“create a molecule that binds X”) into new proteins that fold and function in the lab. We’ve tested 100s already.
PDF here: https://www.bakerlab.org/2022/11/30/diffusion-model-for-protein-design/
🐦🔗: https://twitter.com/_JosephWatson/status/1598409457855496192
Rio Sugimura
bioRxiv
David R. Liu
Benzie's gang ✅