Hey post #menopause friends; have you done #HRT? Did your boobs hurt when you first started? I know it can be a side effect, but I didn't expect it to kick in within 48 hours, and as I tend to catastrophize if I stay in my own head, I thought I'd ask if other women experienced the same.

(For reference; radical hysterectomy, no ovaries present, .25 Estradiol weekly patch, first application yesterday AM)