Give Ubuntu Studio a try maybe? It comes with a lot of audio production stuff preinstalled and preconfigured, one of the most important ones in this context being low-latency process scheduling.

Essentially most distros just have default process scheduling options, which means a process might be starved for CPU time, theoretically for up to 2s or so at a time, which is very bad if that process is generating or consuming an audio stream. Low-latency scheduling, while not entirely preventing it from happening, should significantly reduce this.

You could also just configure most other distros Kernels to do low-latency scheduling of course. Or if you don’t want to muck about with kernel settings try Ubuntu Studio, which has that and more all ready to use.