trendless"What we found, again and again, was that these patients were not treatment resistant in any meaningful psychiatric sense. Their brains were being starved of blood. The sympathetic system was failing to move blood upward, or the parasympathetic system was dilating vessels at exactly the wrong moment, or both. Once you measure the two branches independently and correct the specific imbalance, the so-called depression lifts, not because we treated depression, but because we treated the physiology that was masquerading as depression"
Nearly half of the study cohort (48.3 percent) had been diagnosed with long- or post-COVID syndrome, a population now recognized as a vast and troubled reservoir of autonomic dysfunction.
Treating autonomic dysfunction can relieve symptoms of treatment-resistant depression
Consider a house with the water main half shut. The faucets sputter. The toilet runs all night. The garden wilts. You could call a plumber for the faucet, a landscaper for the garden, a different plumber for the toilet, and every one of them would fix something while fixing nothing.
J. R. DePriest 
:EA DATA. SF:
PapyrusBrigade
Gurre Vildskägg
Chris Goss