đŸ“° "The cytoskeleton contributes to abnormal genome-lamina interactions in LMNA-deficient cardiomyocytes"
https://doi.org/doi:10.1083/jcb.202506137
https://pubmed.ncbi.nlm.nih.gov/41891953/
#Cytoskeleton #Mechanical #Lamin
The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA-deficient cardiomyocytes

Shen et al. demonstrate that LMNA reduction alters peripheral genome organization in human cardiomyocytes through cytoskeletal forces transmitted by the LI

Rockefeller University Press