@SebasFC @Vivaldi no, I haven't tried that yet. You mean the vertical desktop toolbar section, don't you? (I'm on mobile now) I played a bit with it the other day and wound up creating a tool icon for a web site by mistake (that I removed again). So you can customise anything there.
But I'm sure @Vivaldi will reply tomorrow once office hours begin. They're usually active and helpful here on Masto.
To change the Mastodon instance in Vivaldi browser's Web Panel, you need to add your own instance as a new Web Panel and remove Vivaldi Social's Web Panel.
There are a few ways to add Web Panels, but I recommend the following method:
1. Open your instance in a tab and log in.
2. Right-click on an empty area of the web page and select "Add Page to > Add Page to Web Panel".
To remove a Web Panel, right-click on its icon on the sidebar and select "Remove from Toolbar".
You can learn more about Web Panels on https://help.vivaldi.com/desktop/panels/web-panels/.
Hope this helps. 