Ron Beavis ❌
#proteomics_101 SLC25A1:p belongs to the largest family of membrane transport proteins that move metabolites in and out of the mitochondrial matrix through its inner membrane. All of these proteins have 6 transmembrane domains that have fewer bulky hydrophobic residues than TMs in other membranes.
Mar 19 at 12:54pmWeb
Show threadRon Beavis ❌Mar 19
What aspects these proteins life cycles benefit from using small non-polar residues (GAV) in place of bulky non-polar residues (ILFW)? Note: many TM detection algorithms have trouble finding all 6 TMs in these sequences.