@LibertyForward1
Not a screen reader user but I have seen a few posts that stated;

- Please put hashtags at the end of the toot (so screen reader users can skip them if too many)
- Anything over 5 hashtags is just plain dickish
- Capitalize correctly: ShitPost versus shitpost so it can interpolate the individual words (as I recall)

I'm sure there are other points but that is what I recall. Please, if mistaken let me know as I genuinely would strive to improve.