Tardigrades, the toughest animals in the Universe, failed to survive in simulated Martian regolith (surface material).
Researchers tested tardigrades with exposure to martian regolith simulants; their health and activity declined substantially over 4 days. Curiously, they did much better when the regolith was washed, leaching away some of the salts and other chemical compounds.
Testing on plants, animals and humans TBD.

