At very low points, I experience "anhedonic gating," which is the inability to choose a future course of action, because even choosing an action as mundane as one tshirt over another, or one reaction video over another, requires actual dopamine to microsquirt during each evaluating simulation, and the sim with the most squirt wins. My sims are often 100% squirtless, so I just sit there, mulling over beige food and free time options, but never choosing other than randomly.