alphacyberrangerSugar compound from deep-sea bacteria revealed to cause cancer cells to explosively self destruct through pyroptosis
LumisalI imagine this will be similar to chemotherapy.
As in, it technically affects all your cells, it just happens to affect cancer cells a lot more. In this case, because they try to absorb extra sugars in many cases.
gndagrebornCancer cells often times lose their ability to perform oxidative phosphorylation. This means they can only rely on glycolysis as a sole source of ATP… This makes them EXCESSIVELY glucose hungry.
It’s called the warburg effect. I’d have to read up on it and brush up on biochem, but that’s the basic principle.
Essentially, cancer should soak up all the harmful sugar before it hits normal cells. This makes it even safer in theory than traditional chemo like methotrexate and such
PrivateNoobHoly shit Thrive is so good, that I’ve understood most of your terms. Peak game
Another thrive enjoyer in the wild woohoo!
Yeah I’ve only just discovered it some months ago and it looks really promising, although it may never be finished, but I’m glad something like this exists
As I said in another comment, does that mean they can’t get energy from ketone bodies?
As a chemist that makes me wonder why they dont wrap the platinum in sugar complexes
one of my guesses would be that platinum catalysis is expensive as usual, but recovery of the catalyst from living being would be much worse than equivalent lab seetup, so the cost would not justify.
I mean its still in use anyways, so might aswell choose the most direct and selective method if that is via glycocojugates.
Yup, platinum chemo exists already too.
Still makes one feel really nauseated by the second time
because platinum sucks, and if you want to get real selective, you can tie together antibody and something like diphtheria toxin, but it’s not chemistry anymore, that’s firmly in biology ballpark
Because they try to absorb extra sugars in many cases.
I have absolutely no medical knowledge besides a first aid course. Does that mean that, by not eating any sugars, I could starve cancer cells? So like during keto (I did that years ago before the boom) I actually could have starved a lot of cancer cells?
Kinda yeah, though it is better suited as part of a combination therapy.
no because your liver makes sugars anyway. however there’s a more limited, more targeted way to deplete blood of select aminoacids that some cancers can’t make (asparaginase can be used this way)
Yes, certain cancer therapy benefits from a zero sugar, low but high quality carb diet. You’ll slow the cancer a lot, and can help prevent it from coming back like that. You’ll still need something to kill it though, because your body still produces and needs sugars.
And some are unaffected because they’re part of something that can already make or requires sugars, like brain or liver cancers.