Albert Cardona

Glutamate as an inhibitory neurotransmitter in zebrafish – the insect research community welcomes vertebrates into this mess.

"Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors", Anna Ostenrath et al 2024, from Emre Yaksi's lab.

https://www.biorxiv.org/content/10.1101/2024.09.11.612421v1

#neuroscience #glutamate #zebrafish

Sep 13, 2024 at 1:41pmWeb
Show threadmameister4Sep 14, 2024
@albertcardona I thought inhibitory action of glutamate was discovered in vertebrate retina before insects. Shiells RA, Falk G, Naghshineh S (1981). Both mGluRs and glutamatergic Cl-channels, see Grant GB, Dowling JE 1995.
Show threadAlbert CardonaSep 14, 2024

@mameister4

Indeed, was known for sensory systems. Wasn't known, as far as I know, for neurons in the central nervous system.