Teens' brains showed a general effect of accelerated thinning across adolescence, but this was much more pronounced in females. The cortical thinning effects in females were seen all over the brain, in all lobes and both hemispheres.
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https://medicalxpress.com/news/2024-09-covid-lockdowns-prematurely-aged-teenage.html
COVID-19 lockdowns prematurely aged teenage brains, study finds
During the COVID-19 pandemic, governments around the world implemented restrictive measures—such as stay-at-home orders and school closures—to mitigate the spread of the respiratory illness. It's been well-documented that this disruption of daily routines and social activities had a negative impact on the mental health of adolescents.