🐦🔥nemo™🐦⬛ 🇺🇦🍉The Latest Promising #LongCOVID Treatment? #Psychedelic Drugs
Anti. 🐘@nemo I tried psilocybine and weed, both in edible form to be precise. But both of these drugs were taxing on my lungs, which is my main LC issue. And the come down was stressful in both as well.
This might work for some people, maybe also for specific phenotypes of the illness, but it might not be for everyone.
There will not be a silver bullet for #LongCovid
@antiaall3s I see that might be true people are not all the same.
Maybe BC007 can help other people the trials are very promising
https://www.europeanpharmaceuticalreview.com/news/189299/long-covid-study-expanded-across-europe/
https://www.clinicaltrialsarena.com/news/berlin-bc-007-drug-long-covid/
https://www.clinicaltrialsarena.com/news/berlin-cures-long-covid/
Die ganze Welt pilgert nach Mülheim: Therapie-Ansatz gegen "Long-Covid" | SPIEGEL TV
Die ganze Welt pilgert nach Mülheim: Therapie-Ansatz gegen "Long-Covid" | SPIEGEL TV
@nemo The current thinking is that there are different phenotypes (this is the term Medinger/Altman have used in their book The Long COVID Handbook) of this illness. Think of these as clusters of symptoms, that are not even that clear cut in their distinctive features. To complicate things further there might even be overlaps.
But in very! broad strokes: ME/CFS-like symptom clusters is one such cluster, blood coagulation another one and histamine issues a third one.
@nemo Each of these clusters needs a specfic diagnosis and specific treatments. And it needs to be even further differentiated, since what might work for one individual might actually be harmful for another.
This is what all the true experts are saying at the moment: There will not be one silver bullet that helps everyone. What we need is a much more nuanced diagnosis and specific therapies, depending on the pehnotypes.
@antiaall3s Well written I akcnowledge your points.
Short-term: Preventive measures, education, risk assessment (age, immune deficiencies, pre-conditions, etc.) to reduce suffering. Long-term: Tailored individual approach based on phenotypes/symptom clusters, as acknowledged. Genetic susceptibility and regional variations are also valid points. (1/2)
@antiaall3s (2/2)
A holistic approach is crucial, combining prevention, threat modeling (risk factors), and personalized treatment. While tailored therapies are ideal, short-term interventions should also be applied to alleviate suffering.
@nemo There is one further consideration here. Some people are so desperate that they might try anything that is said to be helpful (for some people). Some of these treatments can be pricey, depending on health insurance coverage among other factors. And if we consider that they might not even be helpful depending on the specific phenotype, this becomes tragic.
@antiaall3s People will always try anything to reduce suffering and stay alive. This is hardwired into biology. It is better to try something than to resign. The journey, not the destination, is what has created the success of the human species. An end is nonetheless always there. It is inevitable. What matters is what we do until then. Wer kämpft kann verlieren, wer nicht kämpft hat schon verloren xD Regarding the costs. Human lives are priceless.
@nemo No, i strongly disagree, because of what i said above. Some treatments can actually be harmful. So imagine going into debt for treatments that are actually harmful for you. Tragic. As an example, so many people have paid huge amounts of money for blood washing, but for some their symptoms got worse after.
We gotta be careful to not over-hype any new fad treatment.
@antiaall3s OK, OK I see. Why do we have to pay for this anyway? \U0001f914 Don't we have solidarity? Why aren't the insurance companies paying for it? OK, because there is not enough evidence or data. Why isn't there enough data because there aren't any trials except the BC007 thing which is still ongoing. I totally understand your viewpoint and respect it. "As an example, so many people have paid huge amounts of money for blood washing, but for some their symptoms got worse after."
Source:?
@antiaall3s "We gotta be careful to not over-hype any new fad treatment." Affirmative but this can only be verified or falsified when we have data, or not?
@nemo There are categories of treatments as well.
Of course we are going to try out "cheap" things like Nattokinase [awesome for me!], Pycnogenol, Resveratrol, Quercetin or the like. Diet changes and such.
But there are riskier treatments out there.
And with those riskier ones we need more patience. We need to wait for a. better diagnosis, knowledge of the various phenotypes (because these insights here are still developing) and b. customized treatments.
Which was my point all along.
@nemo As an example, in Hepatitis C for many years there was no cure. Only Interferon, with heavy side effects/very low success rates. Then they started combined treatments with varying other antivirals, with even heavier side effects/not much better success rate.
When in the 2010s a cure was found, with very few side effects, patients who had been feared into doing the combined treatments were no longer eligible for a cure, because the combined treatments had injured their liver too much.
@antiaall3s Let's have a look at the side effect of
H.E.L.P.-Apheresis
H.E.L.P.-Apheresis is generally considered to be a safe and minimally invasive treatment with few reported side effects. Here are the details based on the available information:
Safety and Minimal Invasive Nature:
- H.E.L.P.-Apheresis is considered a safe and minimally invasive treatment that has been carried out for over 30 years, with over 500,000 treatments, of which 200,000 were accompanied scientifically (1/3)
@antiaall3s (2/3)
, and not a single person had severe complications.
- The majority of patients get along well with the treatment and often notice significant improvement of symptoms right after the first session.
Rare Side Effects:
- Rare side effects of H.E.L.P.-Apheresis include temporary and short-term changes in blood pressure and/or dizziness.
- In a study conducted with 20 patients and 955 LDL-apheresis sessions, observed side effects were observed in
@antiaall3s (3/3)
12 percent of all treatment sessions, with hypotension, nausea, hypoglycemia, and light allergic reactions being reported as rare and of minor nature.
Other Considerations:
- The application of H.E.L.P.-Apheresis could significantly contribute to the restoration of microcirculation in the lungs and other affected organs, and it has been successfully applied in various medical conditions.
@nemo Yeah, sure, with that treatment there are other issues (cost!, waiting lists etc.)
But i give up. Keep hyping iffy treatments, i am sure this will do a lot of good.
@antiaall3s Here sources:
https://lcacommunity.org/h-e-l-p-apheresis-faq
https://www.dialysecentrum.de/leistungen/help-apheresis/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361163/
https://www.frontiersin.org/articles/10.3389/fcvm.2022.1007636/full
@nemo Stop spamming me, thank you. I know all this, looked into it, decided it's not for me.