Rxiv mechanobio📰 "α-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2"
by 🔬 Yuou Wang, Alex Yemelyanov, Christopher D Go, Sun Kim, Jeanne M Quinn, Annette S Flozak, Phuong M Le, Shannon Liang, Anne Claude-Gingras, Mitsu Ikura, Noboru Ishiyama, Cara J Gottardi
https://pubmed.ncbi.nlm.nih.gov/37662204/ #Mechanosensitivity #Force #Actin
by 🔬 Yuou Wang, Alex Yemelyanov, Christopher D Go, Sun Kim, Jeanne M Quinn, Annette S Flozak, Phuong M Le, Shannon Liang, Anne Claude-Gingras, Mitsu Ikura, Noboru Ishiyama, Cara J Gottardi
https://pubmed.ncbi.nlm.nih.gov/37662204/ #Mechanosensitivity #Force #Actin
α-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2 - PubMed
Epithelial cells can become polyploid upon tissue injury, but mechanosensitive cues that trigger this state are poorly understood. Using α-catenin (α-cat) knock-out Madin Darby Canine Kidney (MDCK) cells reconstituted with wild-type and mutant forms of α-cat as a model system, we find that an establ …