katch wreck`This report offers fundamental tools and methods for experimental execution and #theoretical analysis of #ultrafast #crystallography. We emphasize the use of phase-space representation of the density matrix using the #Wigner transform to visualize the coherent motions that are seen...These methods are generally applicable, and their purpose is fully demonstrated with this example of ultrafast #structural #dynamics of a reversibly #photoswitching #fluorescent #protein`
Optical control of ultrafast structural dynamics in a fluorescent protein - Nature Chemistry
Pump–probe measurements conventionally achieve femtosecond time resolution for X-ray crystallography of reactive processes, but the measured structural dynamics are complex. Using coherent control techniques, we show that the ultrafast crystallographic differences of a fluorescent protein are dominated by ground-state vibrational processes that are unconnected to the photoisomerization reaction of the chromophore.