iPHoP: An integrated machine learning framework to maximize host prediction for metagenome-derived viruses of archaea and bacteria

The extraordinary diversity of viruses infecting bacteria and archaea is now primarily studied through metagenomics, but information regarding viral hosts is lost. This study presents iPHoP (integrated Phage-Host Prediction), a new tool that leverages multiple complementary approaches to maximize host prediction for metagenome-assembled virus genomes.