“These sulfated steroid hormones, probably altering neurotransmission, produce an increase in longevity, through common factors to germline-less animals. The fact that the enzymes involved in the sulfate modification of steroid hormones ... are expressed in sensory neurons suggests that alteration the sulfated state of hormones may acts in the integration of environmental cues ...with the reproductive status..." https://doi.org/10.1038/s41467-020-20269-y

#aging #longevity #sulfation